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Turning disruptive
targets into
transformational
therapies<\/p>\n

[\/et_pb_cta][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”TK Section” _builder_version=”4.24.2″ _module_preset=”default” custom_padding=”49px||49px||true|false” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row column_structure=”2_5,3_5″ use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|tablet” _builder_version=”4.24.2″ _module_preset=”default” width_tablet=”100%” width_phone=”100%” width_last_edited=”on|tablet” overflow-x=”hidden” overflow-y=”hidden” custom_padding_tablet=”0px|20px|0px|20px|false|false” custom_padding_phone=”|20px|||false|false” global_colors_info=”{}”][et_pb_column type=”2_5″ _builder_version=”4.24.2″ _module_preset=”default” global_colors_info=”{}”][et_pb_heading title=”our unbiased approach” _builder_version=”4.24.2″ _module_preset=”default” title_level=”h2″ title_font=”Nunito Sans|900||on|||||” title_text_color=”#3E92AC” title_font_size=”24px” custom_margin=”25px||12px||false|false” custom_margin_tablet=”0px||||false|false” custom_margin_phone=”0px||||false|false” custom_margin_last_edited=”on|tablet” animation_style=”fade” animation_delay=”1100ms” title_font_size_tablet=”20px” title_font_size_phone=”20px” title_font_size_last_edited=”on|tablet” global_colors_info=”{}”][\/et_pb_heading][et_pb_text _builder_version=”4.24.2″ _module_preset=”default” text_font=”Nunito Sans||||||||” text_text_color=”rgba(0,0,0,0.6)” text_font_size=”20px” text_line_height=”27px” animation_style=”fade” animation_delay=”1100ms” text_font_size_tablet=”18px” text_font_size_phone=”18px” text_font_size_last_edited=”on|tablet” global_colors_info=”{}”]<\/p>\n

Our CRISPRomics\u00ae<\/sup> platform has enabled us to do what no other company had done before—<\/strong>perform genome-scale knockouts across a wide range of immune and cancer cells in disease-relevant models to discover the right targets and develop the right therapies for patients with solid tumors.<\/p>\n

And this was just the beginning.<\/span><\/strong><\/p>\n

Applying an unbiased approach, we were able to leverage our disease models to query >20,000 genes—the entirety of the genome<\/strong>—across more than 600 cancer lines and immune cell types, including T cells, NK cells, and T regulatory cells,<\/strong> to determine which therapeutic targets could be of most benefit to patients. We then discovered and are advancing the most promising therapeutic candidates to fight disease.<\/p>\n

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