{"id":2486,"date":"2022-10-04T13:21:49","date_gmt":"2022-10-04T13:21:49","guid":{"rendered":"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/?page_id=2486"},"modified":"2026-04-28T17:15:40","modified_gmt":"2026-04-28T17:15:40","slug":"publications","status":"publish","type":"page","link":"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\n<div class=\"et_pb_section_0 et_pb_section et_section_regular et_block_section\"><div class=\"et_pb_row_0 et_pb_row et-vb-row--no-module et_block_row\"><div class=\"et_pb_column_0 et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_column_empty et_pb_css_mix_blend_mode_passthrough\"><\/div><\/div><\/div><div class=\"et_pb_section_1 et_pb_section et_section_regular et_block_section\"><div class=\"et_pb_row_1 et_pb_row et_pb_equal_columns et_block_row\"><div class=\"et_pb_column_1 et_pb_column et_pb_column_2_3 et_block_column et_pb_css_mix_blend_mode_passthrough\"><div class=\"et_pb_text_0 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h1 style=\"text-align: left;\"><span class=\"et_pb_fullwidth_header_subhead et-fb-editable-element et-fb-editable-element__editing\" contenteditable=\"true\" data-shortcode-id=\"0.0-1540284059056\" data-quickaccess-id=\"subhead\"><strong>Posters &amp; Publications<\/strong><\/span><\/h1>\n<\/div><\/div><div class=\"et_pb_text_1 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><span style=\"color: #7db2ce;\"><a style=\"color: #7db2ce;\" href=\"https:\/\/evidence.nejm.org\/doi\/full\/10.1056\/EVIDoa2300083\" target=\"_blank\" rel=\"noopener noreferrer\">Nalbuphine Tablets for Cough in Patients with Idiopathic Pulmonary Fibrosis<\/a><\/span><\/h4>\n<p>Maher TM et al.,\u00a0<em>NEJM Evidence<\/em>\u00a0(2023)<\/p>\n<\/div><\/div><div class=\"et_pb_text_2 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><span style=\"color: #7db2ce;\"><a style=\"color: #7db2ce;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36054458\/\" target=\"_blank\" rel=\"noopener noreferrer\">The Role of Kappa-Opioid and Mu-Opioid Receptors in Pruritus: Peripheral and Central Itch Circuits<\/a><\/span><\/h4>\n<p>Kim BS et al.,\u00a0<em>Exp Dermatol.<\/em>\u00a0(2022)<\/p>\n<\/div><\/div><div class=\"et_pb_text_3 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><span style=\"color: #7db2ce;\"><a style=\"color: #7db2ce;\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2666328722000360\" target=\"_blank\" rel=\"noopener noreferrer\">Modulation of the kappa and mu opioid axis for the treatment of chronic pruritus: A review of basic science and clinical implications<\/a><\/span><\/h4>\n<p>Elmariah et al.,\u00a0<em>Journal of the American Academy of Dermatology (JAAD) International<\/em>\u00a0(2021)<\/p>\n<\/div><\/div><div class=\"et_pb_text_4 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><span style=\"color: #7db2ce;\"><a style=\"color: #7db2ce;\" href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1111\/jdv.17816\" target=\"_blank\" rel=\"noopener noreferrer\">Efficacy and safety of oral nalbuphine extended release in prurigo nodularis: results of a phase 2 randomized controlled trial with an open-label extension phase<\/a><\/span><\/h4>\n<p>Weisshaar E. et al.,\u00a0<em>Journal of The European Academy of Dermatology and Venereology<\/em>\u00a0(2021)<\/p>\n<\/div><\/div><div class=\"et_pb_text_5 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><span style=\"color: #7db2ce;\"><a style=\"color: #7db2ce;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34192369\/\" target=\"_blank\" rel=\"noopener noreferrer\">Prevalence, Incidence, and Presence of Comorbidities in Patients with Prurigo and Pruritus in Germany: A Population-Based Claims Data Analysis<\/a><\/span><\/h4>\n<p>Augustin et al.,\u00a0<em>Journal of The European Academy of Dermatology and Venereology<\/em>\u00a0(2021)<\/p>\n<\/div><\/div><div class=\"et_pb_text_6 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><span style=\"color: #7db2ce;\"><a style=\"color: #7db2ce;\" href=\"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-content\/uploads\/2023\/11\/ESDR-21-Liver-Impairment_Poster_Final_09-17-21.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Safety and Pharmacokinetics of Nalbuphine Following Administration of Nalbuphine ER Tablets in Subjects With Impaired Hepatic Function<\/a><\/span><\/h4>\n<p>Rohatagi S. et al.,\u00a0<em>Poster Presentation at European Society for Dermatological Research (ESDR) 50th Annual Meeting<\/em>\u00a0(2021)<\/p>\n<\/div><\/div><div class=\"et_pb_text_7 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><span style=\"color: #7db2ce;\"><a style=\"color: #7db2ce;\" href=\"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-content\/uploads\/2021\/04\/MDD21-Poster_Trevi-Therapeutics_Kim_12-23-20_FINAL.pdf\" _blank=\"\" rel=\"noopener noreferrer\" target=\"_blank\">The Role of Kappa- and Mu- Opioid Receptors in Pruritus <\/a><\/span><\/h4>\n<p>as presented at Maui Derm for Dermatologists 2021<\/p>\n<\/div><\/div><div class=\"et_pb_text_8 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><span style=\"color: #7db2ce;\"><a style=\"color: #7db2ce;\" href=\"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-content\/uploads\/2021\/04\/MDD21-Poster_Trevi-Therapeutics_Elmariah_12-23-20_FINAL.pdf\" _blank=\"\" rel=\"noopener noreferrer\" target=\"_blank\">Modulation of the Mu and Kappa Opioid Axis for Treatment of Chronic Pruritus<\/a><\/span><\/h4>\n<p>as presented at Maui Derm for Dermatologists 2021<\/p>\n<\/div><\/div><div class=\"et_pb_text_9 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><span style=\"color: #7db2ce;\"><a style=\"color: #7db2ce;\" href=\"https:\/\/www.jaadinternational.org\/article\/S2666-3287(20)30067-5\/fulltext\" target=\"_blank\" rel=\"noopener noreferrer\">Prevalence of prurigo nodularis in the United States of America: A retrospective database analysis<\/a><\/span><\/h4>\n<p>St\u00e4nder et al.,\u00a0<em>The American Academy of Dermatology (JAAD) International<\/em> (2020)<\/p>\n<\/div><\/div><div class=\"et_pb_text_10 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><span style=\"color: #7db2ce;\"><a style=\"color: #7db2ce;\" href=\"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-content\/uploads\/2021\/04\/FC20-Poster-Trevi-Therapeutics-Mathur.pdf\" _blank=\"\" rel=\"noopener noreferrer\" target=\"_blank\">A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Nalbuphine ER Tablets for Uremic Pruritus<\/a><\/span><\/h4>\n<p>as presented at the 2020 Fall Clinical Dermatology Conference<\/p>\n<\/div><\/div><div class=\"et_pb_text_11 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><span style=\"color: #7db2ce;\"><a style=\"color: #7db2ce;\" href=\"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-content\/uploads\/2021\/04\/FC20-Poster-Trevi-Therapeutics-Weisshaar.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Efficacy and Safety of Oral Nalbuphine Extended Release in Prurigo Nodularis: Results of a Phase 2, Randomized, Controlled Trial with an Open-Label Extension Phase<\/a><\/span><\/h4>\n<p>as presented at the 2020 Fall Clinical Dermatology Conference<\/p>\n<\/div><\/div><div class=\"et_pb_text_12 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><span style=\"color: #7db2ce;\"><a style=\"color: #7db2ce;\" href=\"https:\/\/www.medicaljournals.se\/acta\/content\/html\/10.2340\/00015555-3518\" target=\"_blank\" rel=\"noopener noreferrer\">Prevalence of Prurigo Nodularis in Poland<\/a><\/span><\/h4>\n<p>Reich and Ryczek,\u00a0<em>Acta Dermato Venereologica<\/em> (2020)<\/p>\n<\/div><\/div><div class=\"et_pb_text_13 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><span style=\"color: #7db2ce;\"><a style=\"color: #7db2ce;\" href=\"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-content\/uploads\/2021\/04\/AAD-2020-Poster-Stander-et-al..pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Prevalence of Prurigo Nodularis in the United States: Findings of a Retrospective Database Analysis<\/a><\/span><\/h4>\n<p>as presented at the 2020 AAD Annual Meeting<\/p>\n<\/div><\/div><div class=\"et_pb_text_14 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><span style=\"color: #7db2ce;\"><a style=\"color: #7db2ce;\" href=\"https:\/\/eprintservices.trustrack.com\/weblink\/d7f5762d685ba7e301685c6cfeda0097\" target=\"_blank\" rel=\"noopener noreferrer\">A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of\u00a0Nalbuphine\u00a0ER Tablets for Uremic\u00a0Pruritus<\/a><\/span><\/h4>\n<p>Mathur et al., <em>American Journal of Nephrology<\/em> (2017)<\/p>\n<\/div><\/div><div class=\"et_pb_text_15 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><a href=\"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-content\/uploads\/2019\/01\/NKF_Poster_SevereSubsetTR02_4-5-16_uploadedtoNKF.pdf\" target=\"blank\" rel=\"attachment wp-att-864 noopener\">Nalbuphine ER Tablets in Hemodialysis Patients with Severe Uremic Pruritus: Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial<\/a><\/h4>\n<p>as presented at the National Kidney Foundation Spring 2016 Meeting.<\/p>\n<\/div><\/div><div class=\"et_pb_text_16 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><a href=\"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-content\/uploads\/2019\/01\/NKF_Poster_TR02ext_uploaded_to_NKF.pdf\" target=\"blank\" rel=\"attachment wp-att-861 noopener\">Long-Term Effects of Nalbuphine ER Tablets in Hemodialysis Patients with Uremic Pruritus: A Multicenter Open-Label Trial<\/a><\/h4>\n<p>as presented at the National Kidney Foundation Spring 2016 Meeting.<\/p>\n<\/div><\/div><div class=\"et_pb_text_17 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><a href=\"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-content\/uploads\/2019\/01\/TR01_PK_BMC_nephrology_2015.pdf\" target=\"blank\" rel=\"attachment wp-att-867 noopener\">Pharmacokinetics of nalbuphine hydrochloride extended release tablets in hemodialysis patients with exploratory effect on pruritus<\/a><\/h4>\n<p>Hawi, et al, <em>BMC Nephrology <\/em>(2015)<\/p>\n<\/div><\/div><div class=\"et_pb_text_18 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><a href=\"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-content\/uploads\/2019\/01\/SID_poster_Trevi_Therapeutics_567_v2.pdf\" target=\"blank\" rel=\"attachment wp-att-897 noopener\">Pharmacokinetics of nalbuphine hydrochloride proof-of-concept study with pharmacokinetics demonstrating anti-pruritic activity of oral nalbuphine in hemodialysis patients with uremic pruritus<\/a><\/h4>\n<p>as presented at the 2014 Meeting of the Society for Investigative Dermatology.<\/p>\n<\/div><\/div><div class=\"et_pb_text_19 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><a href=\"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-content\/uploads\/2019\/01\/ACCP_Poster_1998512_9-8-14_Final_v2.pdf\" target=\"blank\" rel=\"attachment wp-att-901 noopener\">Pharmacokinetics of Nalbuphine Hydrochloride Extended Release Tablets in Hemodialysis and Healthy Subjects following Multiple Escalating Oral Doses<\/a><\/h4>\n<p>as presented at the 2014 Meeting of the American College of Pharmacology.<\/p>\n<\/div><\/div><div class=\"et_pb_text_20 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><a href=\"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-content\/uploads\/2019\/01\/TRV_Nalbuphine_PSTR_ASN_2014-11-06_v2.pdf\" target=\"blank\" rel=\"attachment wp-att-905 noopener\">Exploring Clinical and Pharmacological Effects of Nalbuphine HCl Oral Tablets in Hemodialysis Subjects with Pruritus<\/a><\/h4>\n<p>as presented at\u00a0American Society of Nephrology\u2019s 2014 Kidney Week.<\/p>\n<\/div><\/div><div class=\"et_pb_text_21 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><h4><a href=\"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-content\/uploads\/2019\/01\/Trevi_Itch-Poster_V3-3_v2.pdf\" target=\"blank\" rel=\"attachment wp-att-906 noopener\">Nalbuphine attenuates itch in the substance\u00a0P-induced mouse model<\/a><\/h4>\n<p>as presented at\u00a07th World Congress on Itch (2013).<\/p>\n<\/div><\/div><div class=\"et_pb_module et_pb_button_module_wrapper et_pb_button_0_wrapper\"><a class=\"et_pb_button_0 et_pb_button et_pb_bg_layout_light et_pb_module et_block_module\" href=\"https:\/\/ir.trevitherapeutics.com\">VIEW NEWS<\/a><\/div><\/div><div class=\"et_pb_column_2 et_pb_column et_pb_column_1_3 et-last-child et_block_column et_pb_column_empty et_pb_css_mix_blend_mode_passthrough\"><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-json\/wp\/v2\/pages\/2486"}],"collection":[{"href":"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-json\/wp\/v2\/comments?post=2486"}],"version-history":[{"count":21,"href":"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-json\/wp\/v2\/pages\/2486\/revisions"}],"predecessor-version":[{"id":3286,"href":"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-json\/wp\/v2\/pages\/2486\/revisions\/3286"}],"wp:attachment":[{"href":"https:\/\/s2.designcostaging.com\/clients\/trevitherapeutics\/wp-json\/wp\/v2\/media?parent=2486"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}